王玥

研究方向

主要从事抑郁障碍分子和神经环路机制研究。基于神经炎症、代谢紊乱等角度挖掘抑郁障碍的重要致病分子机制，并结合环路示踪、神经细胞活动及调控技术解析抑郁障碍治病的神经环路机制，寻找抑郁障碍潜在的干预新靶点。以第一作者、通讯作者（含共同）发表SCI论文10篇。国家授权发明专利1项。博士后期间主持中国博士后科学基金项目、重庆市博士后科学基金项目、重庆市博士后特别资助项目，并合作主持重庆医科大学未来医学青年创新团队项目。

代表性论文

1. Yue Wang#, Xiangyu Chen#, Zhi Chen, Heming Yu, Yu Tian, Yong He, Ke Cheng*, Peng Xie*. Disturbances of phosphatidylcholines metabolism in major depressive disorder. CNS Spectr. 2023, 28(5):637-645. doi: 10.1017/S1092852923000020.

2. Yue Wang#, Yan Li#, Zhonghao Wu#, Zhi Chen#, Heming Yu, Yong He, Yu Tian, Tianlan Lan, Mengge Bai, Xiangyu Chen, Ke Cheng*, Peng Xie*. Ferritin disorder in the plasma and hippocampus associated with major depressive disorder. Biochemical and Biophysical Research Communications, 2021,553:114-118.  

3. Yue Wang, Liming Liu, Hengsheng Chen, Li Cheng, Li Jiang*. Influence of the epileptiform discharge microenvironment on the differentiation of oligodendrocyte precursor cells. Brain Research, 2018, 1679:53–63.  

4. Jiashan Xia, Jiayu Wang, Fengyuan Liu, Zhiqiong Chen, Changmei Chen, Xiangshu Cheng, Yu Chao*, Yue Wang*, Tao Deng*. Red/NIR-I-Fluorescence Carbon Dots Based on Rhein with Active Oxygen Scavenging and Colitis Targeting for UC Therap. Adv. Healthcare Mater. 2024, 2304674.

5. Yong He#, Yue Wang#, Heming Yu, Yu Tian, Xiangyu Chen, Chong Chen, Yikun Ren, Zhi Chen, Yi Ren, Xue Gong, Ke Cheng, Xiaolei Liu, Lianmei Zhong*, Yi Guo*, Peng Xie*. Protective effect of Nr4a2 (Nurr1) against LPS-induced depressive-like behaviors via regulating activity of microglia and CamkII neurons in anterior cingulate cortex. Pharmacol Res. 2023, 191:106717.

6. Ke Cheng#, Yue Wang#, Yong He#, Yu Tian#, Junjie Li#, Chong Chen, Xingzhe Xu, Zhonghao Wu, Heming Yu, Xiangyu Chen, Yili Wu, Weihong Song*, Zhifang Dong*, Huatai Xu*, Peng Xie*.Upregulation of carbonic anhydrase 1 beneficial for depressive disorder. Acta Neuropathol Commun. 2023 11(1):59.